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症状：同事打开邮件中的链接，提示：General failure: Application not found.
原因：默认浏览器设置问题
解决方法：Reset the default web browser
Step 11. Click Start, Default Programs
2. Click Set your default programs
3. Select your web browser from the list
4. Click Set this program as default
5. Click OK.
Then follow these steps:
Step 2
1. Click Set program access and computer defaults
2. Click Continue if you see the User Account Control prompt.
3. Click Custom
4. Select your web browser from the list
5. Click OK.
7-16-2012 今天又遇到这个问题，用如下方法解决，默认浏览器是Firefox：
Note: These instructions apply to Windows Vista and 7 only.)
1. Click Start, type regedit, and then press Enter.
2. Navigate to the following entry: HKEY_CLASSES_ROOT\FirefoxURL\shell\open\ddeexec
3. In the center pane, double-click the Default entry, then remove whatever value is there (it'll probably be a weird string of numbers and commas).
4. Click OK, then exit Regedit.
5. If Outlook and/or Firefox are open, close them, then restart them.
本文转simmy51CTO博客，原文链接：http://blog.51cto.com/helpdesk/811436，如需转载请自行联系原作者